Cardioprotection From Cardiotoxicity
نویسندگان
چکیده
منابع مشابه
Cardiotoxicity and cardioprotection in childhood cancer.
Children diagnosed with cancer are now living longer as a result of advances in treatment. However, some commonly used anticancer drugs, although effective in curing cancer, can also cause adverse late effects. The cardiotoxic effects of anthracycline chemotherapy, such as doxorubicin, and radiation can cause persistent and progressive cardiovascular damage, emphasizing a need for effective pre...
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Doxorubicin, used in pediatric chemotherapy regimens, has cardiotoxic effects. Dexrazoxane is co-administrated with doxorubicin to prevent its cardiotoxicity. Here we have explored some alternative food or drugs to be used in absence of dexrazoxane since it’s not readily available in Iran at this time. Keywords: Pediatric, chemotherapy, doxorubicin, cardiotoxicity, dexrazoxane, Iran.
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Anthracyclines are the mainstay of treatment of a variety of haematological malignancies and solid tumours. Unfortunately, the clinical use of these drugs is limited by cumulative, dose-related cardiotoxicity which may ultimately lead to a severe and irreversible form of cardiomyopathy. Thus, there is an increasing need for close cooperation among cardiologists, oncologists and haemato-oncologi...
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Anthracyclines remain among the most widely prescribed and effective anticancer agents. Unfortunately, life-threatening cardiotoxicity continues to compromise their usefulness. Despite more than four decades of investigation, the pathogenic mechanisms responsible for anthracycline cardiotoxicity have not been completely elucidated. In addition, new drugs and combination therapies often exacerba...
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In our just-completed survey of complications following cosmetic surgery, preliminary analysis identified a number of deaths in which lidocaine (Xylocaine) overdosage-the result of multi-liter injection of "tumescent anesthesia" solution (500-1000 mg lidocaine + 1 mg epinephrine per liter)may have played an heretofore unrecognized contributory and perhaps even causative role. Multiliter subcuta...
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ژورنال
عنوان ژورنال: JACC: CardioOncology
سال: 2019
ISSN: 2666-0873
DOI: 10.1016/j.jaccao.2019.08.013